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There is not enough information available to tell whether tacrolimus ointment caused these patients to develop cancer.

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The penetrance of this mutation is approximately 40 per cent, suggesting a possible role for other factors, including environmental factors, in determining disease expression.

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In the absence of enough insulin, fat is broken down for fuel instead.

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Although clinical improvements may be seen in the first few weeks of therapy, medications must be taken regularly for 3 to 4 weeks some 68 weeks before the full therapeutic effect occurs.

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Besides, the new test showed a performance comparable to the acceptable standard methods of our laboratory.

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